By Dr. Marc W. Kirschner, John Norton
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Featuring every little thing Charles Darwin ever wrote approximately fishes and lots of extra subject matters, the entries during this encyclopedia are prepared alphabetically and extracted from Darwin's books, brief courses, notebooks and correspondence. Readers can begin at any place they prefer and are then led through a chain of cross-references at once or ultimately to Darwin's unique writings.
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Additional resources for The Plausibility of Life: Resolving Darwin's Dilemma
It was hard to imagine that random events on their own could create a kind of novelty adaptive to the selective conditions. By direct reference to the ultimate physiological target, pangenesis or any of the other non-Mendelian ideas of directed inheritance avoided the need for stepping-stones to the new phenotype. Attractive as these ideas were, they were completely without foundation. the sources of variation 19 The Disproof of Facilitated Genetic Variation Subsequent years of experimentation brought no support for the direct inheritance of physiological adaptations of the organism to the environment.
The record of living forms also shows a spectrum of anatomies and a parallel spectrum of gene sequences. For example, on a DNA sequence level and on an anatomical level, we are indisputably very closely related to chimpanzees, more distantly related to birds, and even more distantly to ﬁsh. But sequence comparisons can lead us beyond anatomical comparisons. Because DNA sequences can be related across all organisms, they can be used to trace descent into the remote past—even to when we emerged from a bacterial lineage, where no anatomical signposts exist.
These are often involved in controlling the linkage and activity of processes. Although the phenotype may play out at the gross anatomical and physiological level, the real locus of change is in the cellular processes that generate theses anatomies and physiologies. Sewall Wright, the great population geneticist, said it most clearly: “The older writers on evolution were often staggered by the seeming necessity of accounting for the evolution of ﬁne details . . , for example, the ﬁne structure of all the bones .
The Plausibility of Life: Resolving Darwin's Dilemma by Dr. Marc W. Kirschner, John Norton