By A. A. M. Wilde, P. A. Friedman, M. J. Ackerman, W.-K. Shen, Ihor Gussak, Charles Antzelevitch
This e-book presents a different modern and succinct distillation of the present prestige of lately delineated electric ailments of the center, emphasizing their universal and numerous scientific good points. the most recent advancements within the box of experimental and scientific cardiac electrophysiology, genetics, pharmacology and interventional treatments of varied scientific arrhythmogenic entities are featured and mentioned by way of fresh advances in simple and scientific technology. The booklet is split into seven significant elements. every one half involves chapters (total of sixty four) facing similar issues.
Read or Download Electrical Diseases of the Heart: Genetics, Mechanisms, Treatment, Prevention PDF
Similar epidemiology books
Comprises an advent, context and content material of the CDC quarantine station growth plan, present day CDC quarantine stations at US ports of access, bridge from the current to the long run, and extra. comprises a number of appendixes. For public coverage makers. Softcover. DNLM: Quarantine - usa.
In recent times, swift improvement and radical adjustments have happened within the box of breast melanoma examine and therapy. Written via a gaggle of the world over revered researchers and physicians, this booklet stories the knowledge at the moment to be had, identifies parts of controversy and speculates on how the topic might increase within the subsequent decade.
In accordance with findings from a pattern of approximately 1,100 Puerto Ricans residing within the manhattan zone, this ebook posits that adhering to standard cultural values (for instance, the kinfolk) has the socially fascinating final result of discouraging such deviant behaviors as substance abuse. The authors finish that selling particular values won't hinder sure person and social ills; fairly, selling a `sense of culture' itself is required.
This profitable booklet, now in its 3rd variation, keeps to supply a entire advent to the function of epidemiology in veterinary medication. because the booklet of the second one version there was massive enlargement within the software of veterinary epidemiology: extra quantitative tools can be found, demanding situations similar to the epidemic of foot-and-mouth affliction in Europe in 2001 have required epidemiological research, and epidemiological analyses have taken on extra value with the emergence of evidence-based veterinary medication.
- Handbook of Biosurveillance
- The Economics of Epidemiology
- Medicine at the Border: Disease, Globalization and Security, 1850 to the Present
- Sleep disorders and sleep deprivation: an unmet public health problem
- Silent Victories: The History and Practice of Public Health in Twentieth-Century America
- Emerging and Endemic Pathogens: Advances in Surveillance, Detection and Identification
Additional info for Electrical Diseases of the Heart: Genetics, Mechanisms, Treatment, Prevention
Theoretically, generating a cardiac action potential would require an Na+ current, a Ca2+ current, and a K+ current. This is clearly an oversimpliﬁcation. Indeed, the cardiac cell expresses much more different ion currents. 1–3 Thus, the cardiac action potential results from a very complex and ﬁnely tuned interplay of an ensemble of ion channels with different relationships to voltage and time. Only sophisticated computerization can approach the complexity of the cardiac action potential (see below).
21. Makita N, Bennett PB Jr, George AL Jr. Voltagegated Na+ channel beta 1 subunit mRNA expressed in adult human skeletal muscle, heart, and brain is encoded by a single gene. J Biol Chem 1994;269:7571– 7578. 22. Thimmapaya R, Neelands T, Niforatos W, et al. 3 splice variants. Eur J Neurosci 2005; 22:1–9. 23. George AL Jr, Knittle TJ, Tamkun MM. Molecular cloning of an atypical voltage-gated sodium channel expressed in human heart and uterus: Evidence for a distinct gene family. Proc Natl Acad Sci USA 1992;89:4893–4897.
Distribution and prevalence of hyperpolarization-activated cation channel (HCN) mRNA expression in cardiac tissues. Circ Res 1999;85:e1–6. 46. Marionneau C, Couette B, Liu J, et al. Speciﬁc pattern of ionic channel gene expression associated with pacemaker activity in the mouse heart. J Physiol 2005;562:223–234. 47. Hagiwara N, Irisawa H, Kameyama M. Contribution of two types of calcium currents to the pacemaker potentials of rabbit sino-atrial node cells. J Physiol 1988;395:233–253. 48. Brahmajothi MV, Morales MJ, Reimer KA, et al.
Electrical Diseases of the Heart: Genetics, Mechanisms, Treatment, Prevention by A. A. M. Wilde, P. A. Friedman, M. J. Ackerman, W.-K. Shen, Ihor Gussak, Charles Antzelevitch