Clinical Chemistry

Download e-book for iPad: Chemistry and Biology of Hyaluronan by Hari G. Garg, Charles A. Hales

By Hari G. Garg, Charles A. Hales

ISBN-10: 0080443826

ISBN-13: 9780080443829

ISBN-10: 6610967938

ISBN-13: 9786610967933

It was once most likely the French chemist Portes, who first suggested in 1880 that the mucin within the vitreous physique, which he named hyalomucine, behaved in a different way from different mucoids in cornea and cartilage. 54 years later Karl Meyer remoted a brand new polysaccharide from the vitreous, which he named hyaluronic acid. at the present time its legit identify is hyaluronan, and modern day examine in this polysaccharide maintains to develop.

Expertly written by means of prime scientists within the box, this publication presents readers with a extensive, but particular evaluate of the chemistry of hyaluronan, and the position it performs in human biology and pathology. Twenty-seven chapters current a series major from the chemistry and biochemistry of hyaluronan, via its position in a number of pathological stipulations, to converted hylauronans as power healing brokers and at last to the practical, structural and organic houses of hyaluronidases. Chemistry and Biology of Hyaluronan covers the numerous fascinating points of this interesting molecule, and all chapters are meant to arrive the broader examine group. * finished examine the chemistry and biology of hyaluronans * sential to Chemists, Biochemists and clinical researchers * vast but exact overview of this swiftly starting to be study zone

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Additional resources for Chemistry and Biology of Hyaluronan

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Anal Chem 1999; 71:1592 – 1596. 69. Kinoshita M, Okino A, Oda Y, Kakehi K. Anomalous migration of hyaluronic acid oligomers in capillary electrophoresis: correlation to susceptibility to hyaluronidase. Electrophoresis 2001; 22:3458 –3465. 70. Calabro A, Midura R, Wang A, West L, Plaas A, Hascall VC. Fluorophore-assisted carbohydrate electrophoresis (FACE) of glycosaminoglycans. Osteoarthritis Cartilage 2001; 9(Suppl A):S16 – S22. 71. Calabro A, Benavides M, Tammi M, Hascall VC, Midura RJ. Microanalysis of enzyme digests of hyaluronan and chondroitin/dermatan sulfate by fluorophore-assisted carbohydrate electrophoresis (FACE).

The molecular basis of the solution properties of hyaluronan investigated by confocal fluorescence recovery after photobleaching. Biophys J 1999; 77:2210– 2216. 25. Gribbon P, Heng BC, Hardingham TE. The analysis of intermolecular interactions in concentrated hyaluronan solutions suggest no evidence for chain – chain association. Biochem J 2000; 350:329– 335. 26. Engel J. Figure 1 and discussion comment. The biology of hyaluronan. Ciba Found Symp 1989; 143:18– 19. 27. Scott JE, Cummings C, Brass A, Chen Y.

Whistler RL, BeMiller JN. Alkaline degradation of polysaccharides. Adv Carbohydr Chem 1958; 13:289– 329. 56. Holmbeck S, Lerner L. Separation of hyaluronan oligosaccharides by the use of anion-exchange HPLC. Carbohydr Res 1993; 239:239– 244. 57. Midura RJ, Salustri A, Calabro A, Yanagishita M, Hascall VC. High-resolution separation of disaccharide and oligosaccharide alditols from chondroitin sulfate, dermatan sulfate and hyaluronan using CarboPac PA1 chromatography. Glycobiology 1994; 4:333 – 342.

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Chemistry and Biology of Hyaluronan by Hari G. Garg, Charles A. Hales


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