Clinical Chemistry

Get Bioactive natural Products (Part D) PDF

By Atta-ur-Rahman

ISBN-10: 0444506063

ISBN-13: 9780444506061

Usual items play an crucial and ongoing position in selling various features of medical development, and lots of points of simple examine courses are in detail with regards to average items. the importance, as a result, of the reviews in normal Product Chemistry sequence, edited by means of Professor Atta-ur-Rahman, can't be over priced. This quantity, in line with past volumes, provides us with state-of-the-art contributions of significant significance.

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Extra resources for Bioactive natural Products (Part D)

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1 Microorganisms Used in the Screening of SAM BZSAM and 3-MeOSAM Microorganisms ^ SAM 1 BZSAM 3-MeOSAM Metabolite Production ^ Absidia glauca ATCC 22752 ^ 1 SAMM2 1 Achlya racemosa ATCC 11392 (-) 1 Acrasis rosea ATCC 26823 (-) BZSAMMl 1 ^"^ 1 ^"^ NT (-) NT Acrodictys erecta ATCC 24083 (-) (-) NT 1 Acrothecium capsici ATCC 10714 (-) (-) NT 1 Agaricus campestris ATTCC 26815 (-) NT NT Ailomyces arbuscula ATCC 10983 (-) (-) NT 1 Aspergillus alliaceus NRRL 315^ (-) (-) NT Aspergillusflavipes ATCC \OZQ (-) (-) NT Aspergillus flavus}^RRL50\ NT NT 1 Aspergillus flavusHRRL 626 (-) (-) Aspergillus Jumigatus ATCC 26934 (-) NT Aspergillus niger ATCC 10549 (-) NT (-) (-) (-) (-) (-) (-) SAMMl (-) (-) 1 Botrytis alia ATCC 9435 (-) NT NT Bullera alba ATCC l^56S (-) (-) NT Calonectria decora ATCC 14761 (-) NT (-) Candida tropicalis ATCC 20021 NT NT Cantharellus cibarius ATCC 13228 (-) (-) 1 (-) Ceratobasidium cornigerum ATCC 38315 (-) NT NT Chaetomium cochliodes NRRL 2320 (-) NT NT Chlorencoelia versiformis ATCC 24031 (-) NT NT 1 Aspergillus ochraceus ATCC 18500 Aspergillus tamarii NRRL 8101 1 Aureobasidium pullulans ATCC 9348 Beauvarlabassiana ATCC 1159 (-) (-) (-) (-) (-) NT NT NT 1 1 1 1 1 22 KHALED Y.

The Prospective Approach: In this approach the routes of metabolism are first elucidated in microbial systems and then used to predict (and the metabolites facilitate the confirmation of) routes of metabolism in mammals. Also it could be used to explore unanswered questions in mammalian metabolism. For example, microbial studies may reveal a previously undetected mammalian metabolite, elucidate the previously unexplored stereochemical disposition of the xenobiotic in mammalian systems, or be used to study mechanistic aspects concerning the formation of the metabolites.

5)). Structure Elucidation of the Metabolite SAMMl The thermospray mass spectrum of SAMMl indicated that its molecular weight (m/z 410; M^) was the sum of sampangine (232) and a moiety of 178 mass units. A HRFAB mass spectrum of SAMMl showed that exact molecular weight to be consistent with the molecular formula C22H22N2O6. The IR spectrum showed a broad absorption at 3280 cm-^ which suggested the presence of at least one hydroxyl group, while the absence of any strong absorption around 1670 cm-^ region indicated the conversion of the original sampangine carbonyl group into another functionality.

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Bioactive natural Products (Part D) by Atta-ur-Rahman

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